Inhibition of Posterior Capsule Opacification by a Capsular Adhesion–Preventing Ring

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[Posterior capsule opacification, capsular bag distension syndrome, and anterior capsular phimosis: A retrospective cohort study].

OBJECTIVE To determine the incidence and the risk factors involved in the development of the three main postoperative capsular complications: posterior capsule opacification (PCO), capsular bag distension syndrome (CBDS), and anterior capsular phimosis syndrome (ACP). SUBJECTS, MATERIAL AND METHODS A retrospective cohort study was conducted on 801 patients submitted to cataract surgery in the...

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Prevention of posterior capsular opacification through aldose reductase inhibition.

PURPOSE The purpose of this study was to evaluate the effect of aldose reductase (AR) inhibition on posterior capsular opacification (PCO) with the use of a pig eye capsular bag model. METHODS Pig eye capsular bags were prepared by capsulorhexis and cultured in medium without or with AR inhibitors for 7 days. Immunostaining was performed in paraformaldehyde-fixed capsular bags to determine th...

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Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition

PURPOSE To determine if cyclooxygenase-2 (COX-2) is upregulated when lens epithelial cells (LEC) in clinical samples of cataracts and posterior capsule opacification (PCO) undergo epithelial-mesenchymal transition (EMT)-like changes. We also wanted to learn if inhibition of the enzymatic activity of COX-2 could prevent PCO formation. METHODS To ensure that EMT-like changes were occurring in L...

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Posterior Capsule Opacification: An Overview

DOS Times Vol. 12, No. 4 October, 2006 Posterior capsule opacification (PCO) and posterior chamber intraocular lens (PC IOL) decentration still remain two major complications of successful extracapsular cataract surgery (ECCE) or phacoemulsification. Ridley, who performed the first intraocular lens implantation in 1949, himself noted these complications in his earliest patients.7 In his initial...

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Posterior capsule opacification in mice.

OBJECTIVE To present a new model of posterior capsule opacification (PCO) in mice. METHODS An extracapsular lens extraction was performed in 28 consecutive mice. Animals were humanely killed 0 and 24 hours and 3 and 14 days after surgery. Eyes were enucleated and processed for light microscopy and immunohistochemistry. RESULTS In 20 animals (71%), the eye appeared well healed before death. ...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2009

ISSN: 0003-9950

DOI: 10.1001/archophthalmol.2009.63